ISSN: 1300-0330
Dil: Türkçe, İngilizce
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The Rela Tionship Between Classic Atopic Dermatitis And Signs Of Atopy
Doç. Dr .Oya OĞUZ, Prof. Dr .Ertuğrul H. AYDEMİR, Uz.Dr .Gülgün ATİLLA
İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Dermatoloji ABD, İSTANBUL
Generalized or localized forms of atopic dermatitis
(AD) in adulthood may be confusing since skin changes
may simulate contact or irritation dermatitis. On the other
side, another pitfall of diagnosis is the relapsing course of
the disease with minimal/atypic findings of AD, as well.
The rate of occurence of the initial symptoms of classic
atopic dermatitis in adulthood and its relationship with
other signs of atopy was investigated in 117 patients
whose presenting symptoms were: a) Classic atopic dermatitis
(CAD), b) Minimal/atypic atopic dermatitis (MAD)
or c) Constitutional findings of atopy in order to find the
clues for differential diagnosis of AD. No significant difference
existed between the rates of presenting symptoms
(i.e. CAD or MAD) and there was no significant relationship
between the age of beginning and CAD. The rate of
co-existing personel/familial history of atopy was significantly
higher in patients with CAD compared with others
either with MAD or constitutional symptoms (x2=18.50,
p<0.001). Besides, CAD significantly correlated with higher
levels of IgE (p=0.015). The mean age of patients
with late onset CAD was 37.9-7.1 (SD), the incidence
being 1.2%, which indicated that late onset atopic eczema
is not so rare. It was concluded that AD may even
start in late adulthood either presenting with classic or
minimal/atypic forms and the most significant clue for
diagnosis is the history of atopy while high serum levels
of IgE support it.Keywords: Classic atopic dermatitis, Symptoms of atopy,
Age of beginning, HistoryT Klin Dermatoloji 1994, 4:163-167
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